BDBM50134651 (4-Benzyl-piperidin-1-yl)-(6-hydroxy-1H-indol-2-yl)-methanone::(4-benzylpiperidin-1-yl)(6-hydroxy-1H-indol-2-yl)methanone::(4-benzylpiperidine-1-yl)-(6-hydroxy-1H-indole-2-yl)-methanone::CHEMBL333936

SMILES Oc1ccc2cc([nH]c2c1)C(=O)N1CCC(Cc2ccccc2)CC1

InChI Key InChIKey=ZFMWSHBMGFFJML-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50134651   

TargetGlutamate receptor ionotropic, NMDA 2B(Rat)
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50134651((4-Benzyl-piperidin-1-yl)-(6-hydroxy-1H-indol-2-yl...)
Affinity DataIC50: 12nMAssay Description:Displacement of [3H]Ro25-6981 from NR2B NMDA receptor in rat forebrain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2B(Rat)
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50134651((4-Benzyl-piperidin-1-yl)-(6-hydroxy-1H-indol-2-yl...)
Affinity DataIC50: 18nMAssay Description:Antagonist activity at NR2B NMDA receptor in Wistar rat neocortical cells assessed as inhibition of NMDA-evoked elevation of intracellular calcium co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2B(Rat)
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50134651((4-Benzyl-piperidin-1-yl)-(6-hydroxy-1H-indol-2-yl...)
Affinity DataIC50: 12nMAssay Description:Displacement of [3H]Ro 25,6981 from NR2B NMDA receptor in rat forebrainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50134651((4-Benzyl-piperidin-1-yl)-(6-hydroxy-1H-indol-2-yl...)
Affinity DataIC50: 20nMAssay Description:Inhibition of N-methyl-D-aspartate glutamate receptor-evoked increase of intracellular Ca+ in cells expressing NMDA glutamate receptor 1/2BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed