BDBM50134576 6,7,12,13-tetrahydro-5H-pyrido[3',2':4,5]pyrrolo[2,3-a]pyrrolo[4,3-c]carbazole-5,7-dione::CHEMBL338264

SMILES O=C1NC(=O)c2c1c1c3ccc[nH]c3nc1c1[nH]c3ccccc3c21

InChI Key InChIKey=CGVIDEBVTXXEDX-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50134576   

TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Human)
Eli Lilly

Curated by ChEMBL

LigandBDBM50134576(6,7,12,13-tetrahydro-5H-pyrido[3',2':4,5]pyrrolo[2...)Copy SMILESCopy InChI

Affinity DataIC50: 250nMAssay Description:Inhibitory activity against Cyclin D1-cyclin-dependent kinase 4 by measuring the phosphorylation of RbINGMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
11/10/2009
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL