BDBM50134556 4-[(4-Cyano-phenyl)-(3-methyl-3H-imidazol-4-yl)-methoxymethyl]-3-(3,3-dimethyl-butyl)-benzonitrile::CHEMBL124339

SMILES Cn1cncc1C(OCc1ccc(cc1CCC(C)(C)C)C#N)c1ccc(cc1)C#N

InChI Key InChIKey=HPTPUWFOBXCUAN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50134556   

LigandPNGBDBM50134556(4-[(4-Cyano-phenyl)-(3-methyl-3H-imidazol-4-yl)-me...)
Affinity DataIC50: 310nMAssay Description:In vitro inhibition of the human Geranylgeranyl transferase-catalyzed incorporation of [3H]GGPP into biotinylated peptide corresponding to the C-term...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50134556(4-[(4-Cyano-phenyl)-(3-methyl-3H-imidazol-4-yl)-me...)
Affinity DataIC50: 0.950nMAssay Description:In vitro inhibition of the human FTase-catalyzed incorporation of [3H]FPP into recombinant Ras CVIM.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed