BDBM50134555 4-[(4-Cyano-phenyl)-(3-methyl-3H-imidazol-4-yl)-methoxymethyl]-3-(3-hydroxy-phenylethynyl)-benzonitrile::CHEMBL421641

SMILES Cn1cncc1C(OCc1ccc(cc1C#Cc1cccc(O)c1)C#N)c1ccc(cc1)C#N

InChI Key InChIKey=RFDWGJYINANKTJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50134555   

LigandPNGBDBM50134555(4-[(4-Cyano-phenyl)-(3-methyl-3H-imidazol-4-yl)-me...)
Affinity DataIC50: 1.30E+3nMAssay Description:In vitro inhibition of the human Geranylgeranyl transferase-catalyzed incorporation of [3H]GGPP into biotinylated peptide corresponding to the C-term...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50134555(4-[(4-Cyano-phenyl)-(3-methyl-3H-imidazol-4-yl)-me...)
Affinity DataIC50: 1nMAssay Description:In vitro inhibition of the human FTase-catalyzed incorporation of [3H]FPP into recombinant Ras CVIM.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed