BDBM50134378 (2S)-5-{[(Z)-amino(imino)methyl]amino}-2-(methylamino)pentanoic acid::(2S)-5-{[amino(imino)methyl]amino}-2-(methylamino)pentanoic acid::(S)-5-Guanidino-2-methylamino-pentanoic acid::(S)-5-guanidino-2-(methylamino)pentanoic acid::CHEMBL332148::N-Monomethyl-L-arginine::N~5~-(DIAMINOMETHYLENE)-N~2~-METHYLORNITHINE

SMILES [#6]-[#7]-[#6@@H](-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7])-[#6](-[#8])=O

InChI Key InChIKey=NWJKAYCJSUPWTK-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50134378   

TargetNitric oxide synthase, brain(Human)
Dainippon Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50134378((S)-5-Guanidino-2-methylamino-pentanoic acid | (S)...)
Affinity DataIC50: 4.30E+3nMAssay Description:Inhibitory concentration against neuronal nitric acid synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Human)
Dainippon Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50134378((S)-5-Guanidino-2-methylamino-pentanoic acid | (S)...)
Affinity DataIC50: 1.90E+4nMAssay Description:Inhibitory concentration against inducible nitric acid synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Human)
Dainippon Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50134378((S)-5-Guanidino-2-methylamino-pentanoic acid | (S)...)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of human iNOS expressed in baculovirus-infected insect sf9 cells assessed as conversion of [3H]-L-arginine to [3H]-L-citrulline preincubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Human)
Dainippon Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50134378((S)-5-Guanidino-2-methylamino-pentanoic acid | (S)...)
Affinity DataIC50: 950nMAssay Description:Inhibition of human nNOS expressed in baculovirus-infected insect sf9 cells assessed as conversion of [3H]-L-arginine to [3H]-L-citrulline preincubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial(Human)
Neuraxon

Curated by ChEMBL
LigandPNGBDBM50134378((S)-5-Guanidino-2-methylamino-pentanoic acid | (S)...)
Affinity DataIC50: 650nMAssay Description:Inhibition of human eNOS expressed in baculovirus-infected insect sf9 cells assessed as conversion of [3H]-L-arginine to [3H]-L-citrulline preincubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed