BDBM50134351 4-Hydroxy-3,5-dimethyl-5-(3-phenoxy-benzyl)-5H-thiophen-2-one::CHEMBL332364

SMILES CC1C(=O)SC(C)(Cc2cccc(Oc3ccccc3)c2)C1=O

InChI Key InChIKey=NVAFOHJQQOQWCN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50134351   

Target3-oxoacyl-[acyl-carrier-protein] synthase 3(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
The University of Birmingham

Curated by ChEMBL
LigandPNGBDBM50134351(4-Hydroxy-3,5-dimethyl-5-(3-phenoxy-benzyl)-5H-thi...)
Affinity DataIC50: 5.20E+4nMAssay Description:In vitro inhibitory activity against the recombinant Mycobacterium tuberculosis Beta-ketoacyl-ACP synthase III mtFabH condensing enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed