BDBM50134333 CHEMBL331089::Phenyl-acetic acid (1R,3R,5S)-8-(3,5-bis-trifluoromethyl-benzenesulfonylaminocarbonyl)-8-aza-bicyclo[3.2.1]oct-3-yl ester::Phenyl-acetic acid (1S,3R,5R)-8-(3,5-bis-trifluoromethyl-benzenesulfonylaminocarbonyl)-8-aza-bicyclo[3.2.1]oct-3-yl ester

SMILES FC(F)(F)c1cc(cc(c1)S(=O)(=O)NC(=O)N1[C@H]2CC[C@@H]1C[C@@H](C2)OC(=O)Cc1ccccc1)C(F)(F)F

InChI Key

Data  2 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50134333   

TargetSteryl-sulfatase(Human)
Novartis Research Institute Vienna

Curated by ChEMBL
LigandPNGBDBM50134333(Phenyl-acetic acid (1S,3R,5R)-8-(3,5-bis-trifluoro...)
Affinity DataIC50: 84nMAssay Description:Inhibitory activity against purified human Steroid sulfataseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSteryl-sulfatase(Human)
Novartis Research Institute Vienna

Curated by ChEMBL
LigandPNGBDBM50134333(Phenyl-acetic acid (1S,3R,5R)-8-(3,5-bis-trifluoro...)
Affinity DataIC50: 84nMAssay Description:Inhibitory concentration against human steroid sulfataseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSteryl-sulfatase(Human)
Novartis Research Institute Vienna

Curated by ChEMBL
LigandPNGBDBM50134333(Phenyl-acetic acid (1S,3R,5R)-8-(3,5-bis-trifluoro...)
Affinity DataIC50: 1.89E+3nMAssay Description:Inhibitory concentration against human steroid sulfatase expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSteryl-sulfatase(Human)
Novartis Research Institute Vienna

Curated by ChEMBL
LigandPNGBDBM50134333(Phenyl-acetic acid (1S,3R,5R)-8-(3,5-bis-trifluoro...)
Affinity DataIC50: 1.89E+3nMAssay Description:Inhibitory activity against Steroid sulfatase expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSteryl-sulfatase(Human)
Novartis Research Institute Vienna

Curated by ChEMBL
LigandPNGBDBM50134333(Phenyl-acetic acid (1S,3R,5R)-8-(3,5-bis-trifluoro...)
Affinity DataKi:  76nMAssay Description:Inhibitory constant against human steroid sulfataseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSteryl-sulfatase(Human)
Novartis Research Institute Vienna

Curated by ChEMBL
LigandPNGBDBM50134333(Phenyl-acetic acid (1S,3R,5R)-8-(3,5-bis-trifluoro...)
Affinity DataKi:  76nMAssay Description:Inhibitory constant against purified human Steroid sulfataseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed