BDBM50134170 1-((S)-2-Cyclopentanecarbonyl-pyrrolidin-1-yl)-5-{(S)-2-[(S)-2-(2-hydroxy-acetyl)-pyrrolidine-1-carbonyl]-pyrrolidin-1-yl}-3,3-dimethyl-pentane-1,5-dione::CHEMBL435223

SMILES CC(C)(CC(=O)N1CCC[C@H]1C(=O)C1CCCC1)CC(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)CO

InChI Key InChIKey=GSZHMPLZQUQVSY-UHFFFAOYSA-N

Data  3 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50134170   

TargetProlyl endopeptidase(Pig)
University of Kuopio

Curated by ChEMBL
LigandPNGBDBM50134170(1-((S)-2-Cyclopentanecarbonyl-pyrrolidin-1-yl)-5-{...)
Affinity DataIC50: 0.320nMAssay Description:In vitro inhibition of prolyl oligopeptidase (POP) from pig brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProlyl endopeptidase(Pig)
University of Kuopio

Curated by ChEMBL
LigandPNGBDBM50134170(1-((S)-2-Cyclopentanecarbonyl-pyrrolidin-1-yl)-5-{...)
Affinity DataIC50: 0.320nMpH: 7.0Assay Description:In vitro inhibitory activity against porcine prolyl oligopeptidase by using 4 mM Suc-Gly-Pro-7-amido-4-methylcoumarin as substrate (pH 7.0) at 30 deg...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetProlyl endopeptidase(Human)
University of Helsinki

Curated by ChEMBL
LigandPNGBDBM50134170(1-((S)-2-Cyclopentanecarbonyl-pyrrolidin-1-yl)-5-{...)
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetProlyl endopeptidase(Human)
University of Helsinki

Curated by ChEMBL
LigandPNGBDBM50134170(1-((S)-2-Cyclopentanecarbonyl-pyrrolidin-1-yl)-5-{...)
Affinity DataKd:  90nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed