BDBM50133927 1-(4-Fluoro-phenyl)-3-(1,2,4,4a,5,6-hexahydro-pyrazino[1,2-a]quinolin-3-yl)-propan-1-one::CHEMBL345106

SMILES Fc1ccc(cc1)C(=O)CCN1CCN2C(CCc3ccccc23)C1

InChI Key InChIKey=DOHBWZBXSGIRIR-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50133927   

TargetD(3) dopamine receptor(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50133927(1-(4-Fluoro-phenyl)-3-(1,2,4,4a,5,6-hexahydro-pyra...)
Affinity DataKi:  465nMAssay Description:Ability to compete with [3H]YM-09151-2 binding to the human dopamine receptor D3 transfected in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Rat)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50133927(1-(4-Fluoro-phenyl)-3-(1,2,4,4a,5,6-hexahydro-pyra...)
Affinity DataKi:  2.76E+3nMAssay Description:Binding affinity D3 [3H]-PD 128907 receptor was determined using caudate-putamen of adult male Spragueo=Dawley ratsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed