BDBM50133731 CHEMBL118988::{3-[3-(4-Cyano-3-methoxy-phenyl)-ureido]-benzyl}-carbamic acid (R)-2-cyano-1-ethyl-ethyl ester

SMILES CC[C@H](CC#N)OC(=O)NCc1cccc(NC(=O)Nc2ccc(C#N)c(OC)c2)c1

InChI Key InChIKey=GIXCDHPRXDBJBN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50133731   

TargetInosine-5'-monophosphate dehydrogenase 2(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50133731({3-[3-(4-Cyano-3-methoxy-phenyl)-ureido]-benzyl}-c...)
Affinity DataIC50: 6nMAssay Description:Inhibitory activity tested against inosine-5'-monophosphate dehydrogenase 2 (IMPDH-II) enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed