BDBM50133727 1-(3-Cyano-1-methyl-1H-indol-6-yl)-3-phenyl-urea::1-(3-cyano-1-methyl-1H-indol-6-yl)-3-phenylurea::CHEMBL333482

SMILES Cn1cc(C#N)c2ccc(NC(=O)Nc3ccccc3)cc12

InChI Key InChIKey=DKHWZIZMXRFFLI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50133727   

TargetInosine-5'-monophosphate dehydrogenase 2(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50133727(1-(3-Cyano-1-methyl-1H-indol-6-yl)-3-phenyl-urea |...)
Affinity DataIC50: 630nMAssay Description:Inhibitory activity tested against inosine-5'-monophosphate dehydrogenase 2 (IMPDH-II) enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50133727(1-(3-Cyano-1-methyl-1H-indol-6-yl)-3-phenyl-urea |...)
Affinity DataIC50: 722nMAssay Description:Inhibition of IMPDH2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed