BDBM50133660 5-{3-[3-(4-Cycloheptyl-2-propyl-phenoxy)-propoxy]-phenyl}-oxazolidine-2,4-dione::CHEMBL118251::CHEMBL1783054

SMILES CCCc1cc(ccc1OCCCOc1cccc(c1)-c1oc(=O)[nH]c1O)C1CCCCCC1

InChI Key InChIKey=NCPUHZJZRNXHPV-UHFFFAOYSA-N

Data  4 IC50  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50133660   

TargetPeroxisome proliferator-activated receptor delta(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50133660(CHEMBL118251 | CHEMBL1783054 | 5-{3-[3-(4-Cyclohep...)
Affinity DataIC50: 5.00E+4nMAssay Description:In vitro binding affinity was tested towards human Peroxisome proliferator activated receptor deltaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50133660(CHEMBL118251 | CHEMBL1783054 | 5-{3-[3-(4-Cyclohep...)
Affinity DataIC50: 610nMAssay Description:In vitro binding affinity was tested towards human Peroxisome proliferator activated receptor alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50133660(CHEMBL118251 | CHEMBL1783054 | 5-{3-[3-(4-Cyclohep...)
Affinity DataIC50: 640nMAssay Description:In vitro binding affinity against human peroxisome proliferator activated receptor gammaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50133660(CHEMBL118251 | CHEMBL1783054 | 5-{3-[3-(4-Cyclohep...)
Affinity DataIC50: 640nMAssay Description:Displacement of radio-labeled full agonist from PPARgamma receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2011
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50133660(CHEMBL118251 | CHEMBL1783054 | 5-{3-[3-(4-Cyclohep...)
Affinity DataEC50:  35nMAssay Description:In vitro activity in human peroxisome proliferator activated receptor gamma-transactivation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50133660(CHEMBL118251 | CHEMBL1783054 | 5-{3-[3-(4-Cyclohep...)
Affinity DataEC50:  54nMAssay Description:In vitro activity in human Peroxisome proliferator activated receptor alpha-transactivation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor delta(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50133660(CHEMBL118251 | CHEMBL1783054 | 5-{3-[3-(4-Cyclohep...)
Affinity DataEC50: >3.00E+3nMAssay Description:In vitro activity in human Peroxisome proliferator activated receptor delta-transactivation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed