BDBM50133627 (3Z)-5-nitro-1H-indole-2,3-dione 3-thiosemicarbazone::CHEMBL120254

SMILES NC([S-])=[N+]=Nc1c2cc(cc[c-]2[nH]c1=[OH+])[N+]([O-])=O

InChI Key InChIKey=BOFXWAAUQQURPA-UHFFFAOYSA-O

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50133627   

TargetCruzipain(Trypanosoma cruzi)
University of Cape Town

Curated by ChEMBL
LigandPNGBDBM50133627((3Z)-5-nitro-1H-indole-2,3-dione 3-thiosemicarbazo...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibitory activity against the Trypanosoma cruzi cysteine protease cruzainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetFalcipain 2(malaria parasite P. falciparum)
University of Cape Town

Curated by ChEMBL
LigandPNGBDBM50133627((3Z)-5-nitro-1H-indole-2,3-dione 3-thiosemicarbazo...)
Affinity DataIC50: 4.40E+3nMAssay Description:Inhibitory activity against Falcipain-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCruzipain(Trypanosoma cruzi)
University of Cape Town

Curated by ChEMBL
LigandPNGBDBM50133627((3Z)-5-nitro-1H-indole-2,3-dione 3-thiosemicarbazo...)
Affinity DataIC50: 1.70E+4nMAssay Description:Inhibitory activity against Trypanosoma brucei rhodesiense cysteine protease rhodesainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed