BDBM50133626 (3Z)-5,7-dimethyl-1H-indole-2,3-dione 3-thiosemicarbazone::CHEMBL118210

SMILES Cc1cc(C)c2[nH]c(O)c(N=NC(N)=S)c2c1

InChI Key InChIKey=HTDJZMISNHTPTM-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50133626   

TargetFalcipain 2(malaria parasite P. falciparum)
University of Cape Town

Curated by ChEMBL
LigandPNGBDBM50133626((3Z)-5,7-dimethyl-1H-indole-2,3-dione 3-thiosemica...)
Affinity DataIC50: 1.32E+4nMAssay Description:Inhibitory activity against Falcipain-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCruzipain(Trypanosoma cruzi)
University of Cape Town

Curated by ChEMBL
LigandPNGBDBM50133626((3Z)-5,7-dimethyl-1H-indole-2,3-dione 3-thiosemica...)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibitory activity against Trypanosoma brucei rhodesiense cysteine protease rhodesainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCruzipain(Trypanosoma cruzi)
University of Cape Town

Curated by ChEMBL
LigandPNGBDBM50133626((3Z)-5,7-dimethyl-1H-indole-2,3-dione 3-thiosemica...)
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibitory activity against the Trypanosoma cruzi cysteine protease cruzainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed