BDBM50133619 (3Z)-5-chloro-7-methyl-1H-indole-2,3-dione 3-thiosemicarbazone::CHEMBL118355

SMILES Cc1cc(Cl)cc2c(N=NC(N)=S)c(O)[nH]c12

InChI Key InChIKey=JWOYEHHAFIQJFI-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50133619   

TargetCruzipain(Trypanosoma cruzi)
University of Cape Town

Curated by ChEMBL
LigandPNGBDBM50133619((3Z)-5-chloro-7-methyl-1H-indole-2,3-dione 3-thios...)
Affinity DataIC50: 1.05E+4nMAssay Description:Inhibitory activity against the Trypanosoma cruzi cysteine protease cruzainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetFalcipain 2(malaria parasite P. falciparum)
University of Cape Town

Curated by ChEMBL
LigandPNGBDBM50133619((3Z)-5-chloro-7-methyl-1H-indole-2,3-dione 3-thios...)
Affinity DataIC50: 9.40E+3nMAssay Description:Inhibitory activity against Falcipain-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCruzipain(Trypanosoma cruzi)
University of Cape Town

Curated by ChEMBL
LigandPNGBDBM50133619((3Z)-5-chloro-7-methyl-1H-indole-2,3-dione 3-thios...)
Affinity DataIC50: 1.05E+4nMAssay Description:Inhibitory activity against the Trypanosoma cruzi cysteine protease cruzainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed