BDBM50133603 CHEMBL3633248

SMILES COc1ccc(c(OC)c1)-c1cc(=O)[nH]c(=S)n1CC(N)=O

InChI Key InChIKey=GQWZBUKEJKGQTB-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50133603   

TargetMyeloperoxidase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50133603(CHEMBL3633248)
Affinity DataIC50: 2.60E+3nMAssay Description:Irreversible inhibition of MPO in LPS-stimulated human whole blood after 4 hrs by Amplex Red/H2O2-based fluorescence plate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2016
Entry Details Article
PubMed
TargetMyeloperoxidase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50133603(CHEMBL3633248)
Affinity DataKi:  372nMAssay Description:Inhibition of peroxidase activity of MPO isolated from human polynuclear leukocytes using Amplex Red as substrate assessed as formation of resorufin ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2016
Entry Details Article
PubMed