BDBM50133573 CHEMBL119530::N-[2-(2,6-dichlorobenzyl)-1,3-thiazol-4-yl]-N'-phenoxyurea

SMILES Clc1cccc(Cl)c1Cc1nc(NC(=O)NOc2ccccc2)cs1

InChI Key InChIKey=KZAAPNQFAUCLEX-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50133573   

TargetCyclin-dependent kinase 5 activator 1(Human)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50133573(N-[2-(2,6-dichlorobenzyl)-1,3-thiazol-4-yl]-N'-phe...)
Affinity DataIC50: 900nMAssay Description:Ability to inhibit Cyclin-dependent kinase 5-p35.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50133573(N-[2-(2,6-dichlorobenzyl)-1,3-thiazol-4-yl]-N'-phe...)
Affinity DataIC50: 1.00E+5nMAssay Description:Ability to inhibit cyclin-dependent kinase 2-cyclin A.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50133573(N-[2-(2,6-dichlorobenzyl)-1,3-thiazol-4-yl]-N'-phe...)
Affinity DataIC50: 900nMAssay Description:Inhibition of CDK5/p25 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50133573(N-[2-(2,6-dichlorobenzyl)-1,3-thiazol-4-yl]-N'-phe...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of CDK2/cyclin A (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed