BDBM50133516 3-(4-Aminomethyl-phenyl)-N-cyclopentyl-2-(6-methoxy-naphthalene-2-sulfonylamino)-N-methyl-propionamide::CHEMBL334257

SMILES COc1ccc2cc(ccc2c1)S(=O)(=O)NC(Cc1ccc(CN)cc1)C(=O)N(C)C1CCCC1

InChI Key InChIKey=BDMUHVMXOXBHES-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50133516   

TargetProthrombin(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50133516(3-(4-Aminomethyl-phenyl)-N-cyclopentyl-2-(6-methox...)
Affinity DataKi:  6.60nMAssay Description:Inhibitory constant evaluated against thrombin (Factor IIa)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine protease 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50133516(3-(4-Aminomethyl-phenyl)-N-cyclopentyl-2-(6-methox...)
Affinity DataKi:  1.42E+4nMAssay Description:Inhibitory constant evaluated against trypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed