BDBM50133473 CHEMBL3632994

SMILES Cc1c(C)c2OC(C)(CCc2c(C)c1O)C(=O)NCCCCCCCCNc1c2CCCCc2nc2cc(Cl)ccc12

InChI Key InChIKey=MATYDNFWBAVIBC-UHFFFAOYSA-N

Data  1 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50133473   

TargetAcetylcholinesterase(Human)
University Hospital Hradec Kralove

Curated by ChEMBL
LigandPNGBDBM50133473(CHEMBL3632994)
Affinity DataIC50: 80nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine as substrate preincubated for 5 mins followed by substrate addition measured every 2 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2016
Entry Details Article
PubMed
TargetCholinesterase(Human)
University Hospital Hradec Kralove

Curated by ChEMBL
LigandPNGBDBM50133473(CHEMBL3632994)
Affinity DataIC50: 540nMAssay Description:Inhibition of human plasmatic BChE using butyrylthiocholine as substrate preincubated for 5 mins followed by substrate addition measured every 2 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2016
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
University Hospital Hradec Kralove

Curated by ChEMBL
LigandPNGBDBM50133473(CHEMBL3632994)
Affinity DataIC50: 80nMAssay Description:Inhibition of Ache (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/2/2019
Entry Details Article
PubMed
TargetCholinesterase(Human)
University Hospital Hradec Kralove

Curated by ChEMBL
LigandPNGBDBM50133473(CHEMBL3632994)
Affinity DataIC50: 54nMAssay Description:Inhibition of BuChE (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/2/2019
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
University Hospital Hradec Kralove

Curated by ChEMBL
LigandPNGBDBM50133473(CHEMBL3632994)
Affinity DataKi:  50nMAssay Description:Competitive inhibition of human recombinant AChE using acetylthiocholine as substrate preincubated for 5 mins followed by substrate addition measured...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2016
Entry Details Article
PubMed