BDBM50133367 CHEMBL341777::N-(2-Furan-2-yl-8-phenethyl-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-yl)-2-phenoxy-acetamide

SMILES O=C(COc1ccccc1)Nc1nc2nn(CCc3ccccc3)cc2c2nc(nn12)-c1ccco1

InChI Key InChIKey=PXLNNXUUFHRPRE-UHFFFAOYSA-N

Data  5 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50133367   

TargetAdenosine receptor A2b(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50133367(N-(2-Furan-2-yl-8-phenethyl-8H-pyrazolo[4,3-e][1,2...)
Affinity DataIC50: 130nMAssay Description:Inhibitory activity against NECA stimulated cAMP accumulation in CHO cells expressing human adenosine A2B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50133367(N-(2-Furan-2-yl-8-phenethyl-8H-pyrazolo[4,3-e][1,2...)
Affinity DataKi:  20nMAssay Description:Displacement of [3H]DPCPX from human Adenosine A1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A2b(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50133367(N-(2-Furan-2-yl-8-phenethyl-8H-pyrazolo[4,3-e][1,2...)
Affinity DataKi:  22nMAssay Description:Displacement of [3H]DPCPX from human adenosine A2B receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50133367(N-(2-Furan-2-yl-8-phenethyl-8H-pyrazolo[4,3-e][1,2...)
Affinity DataKi:  40nMAssay Description:Displacement of [3H]ZM-241385 from human adenosine A2A receptors expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50133367(N-(2-Furan-2-yl-8-phenethyl-8H-pyrazolo[4,3-e][1,2...)
Affinity DataKi:  300nMAssay Description:Displacement of [3H]MRE3008-F20 from human A3 receptors expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50133367(N-(2-Furan-2-yl-8-phenethyl-8H-pyrazolo[4,3-e][1,2...)
Affinity DataKi:  300nMAssay Description:Antagonist activity at human adenosine A3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed