BDBM50132930 CHEMBL325918::[3-(2,4-Dichloro-phenyl)-1,5-dimethyl-1H-pyrazolo[4,3-b]pyridin-7-yl]-bis-(2-methoxy-ethyl)-amine

SMILES COCCN(CCOC)c1cc(C)nc2c(nn(C)c12)-c1ccc(Cl)cc1Cl

InChI Key InChIKey=FHTOTHHKXBXMIN-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50132930   

TargetCorticotropin-releasing factor receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50132930([3-(2,4-Dichloro-phenyl)-1,5-dimethyl-1H-pyrazolo[...)
Affinity DataIC50: 38nMAssay Description:Inhibition of Corticotropin releasing factor receptor 1-stimulated cAMP productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50132930([3-(2,4-Dichloro-phenyl)-1,5-dimethyl-1H-pyrazolo[...)
Affinity DataKi:  8.20nMAssay Description:Inhibition of (Corticotropin-Releasing Factor Receptor) CRF-stimulated cAMP productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed