BDBM50132927 Butyl-cyclopropylmethyl-[3-(2,4-dichloro-phenyl)-1,5-dimethyl-1H-pyrazolo[4,3-b]pyridin-7-yl]-amine::CHEMBL432976

SMILES CCCCN(CC1CC1)c1cc(C)nc2c(nn(C)c12)-c1ccc(Cl)cc1Cl

InChI Key InChIKey=MTOPYAFHQJAORJ-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50132927   

TargetCorticotropin-releasing factor receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50132927(Butyl-cyclopropylmethyl-[3-(2,4-dichloro-phenyl)-1...)
Affinity DataIC50: 3nMAssay Description:Inhibition of Corticotropin releasing factor receptor 1-stimulated cAMP productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50132927(Butyl-cyclopropylmethyl-[3-(2,4-dichloro-phenyl)-1...)
Affinity DataKi:  1.30nMAssay Description:Inhibition of (Corticotropin-Releasing Factor Receptor) CRF-stimulated cAMP productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed