BDBM50132777 CHEMBL3634427

SMILES Cc1ccoc1C(=O)Nc1ccc(N2C(=O)c3cccc(C)c3C2=O)c(c1)C(F)(F)F

InChI Key InChIKey=CVOJZCARFHUPQD-UHFFFAOYSA-N

Data  1 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50132777   

TargetMetabotropic glutamate receptor 1(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50132777(CHEMBL3634427)
Affinity DataEC50:  530nMAssay Description:Positive allosteric modulation of human mGluR1 by calcium mobilization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2016
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50132777(CHEMBL3634427)
Affinity DataIC50: 537nMAssay Description:Positive allosteric modulation of human mGluR1 by calcium mobilization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2016
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50132777(CHEMBL3634427)
Affinity DataEC50:  5.76E+3nMAssay Description:Positive allosteric modulation of human mGluR4 by calcium mobilization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2016
Entry Details Article
PubMed