BDBM50132715 CHEMBL97038::Dodecanesulfonyl fluoride::dodecane-1-sulfonyl fluoride

SMILES CCCCCCCCCCCCS(F)(=O)=O

InChI Key InChIKey=UVLRFDMRDPQRSM-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50132715   

TargetCannabinoid receptor 1(Mouse)
University of California

Curated by ChEMBL
LigandPNGBDBM50132715(Dodecanesulfonyl fluoride | dodecane-1-sulfonyl fl...)
Affinity DataIC50: 6.90nMAssay Description:Binding affinity towards Cannabinoid receptor 1 was determined using [3H]-CP- cannabinoid as radioligand with mouse brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Mouse)
University of California

Curated by ChEMBL
LigandPNGBDBM50132715(Dodecanesulfonyl fluoride | dodecane-1-sulfonyl fl...)
Affinity DataIC50: 2nMAssay Description:Inhibitory potency of Fatty-acid amide hydrolase with Mouse brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rat)
University of California

Curated by ChEMBL
LigandPNGBDBM50132715(Dodecanesulfonyl fluoride | dodecane-1-sulfonyl fl...)
Affinity DataIC50: 3nMAssay Description:Inhibitory potency of Fatty-acid amide hydrolase with rat brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Rat)
University of California

Curated by ChEMBL
LigandPNGBDBM50132715(Dodecanesulfonyl fluoride | dodecane-1-sulfonyl fl...)
Affinity DataIC50: 18nMAssay Description:Binding affinity towards Cannabinoid receptor 1 was determined using [3H]-CP- cannabinoid as radioligand with rat brain membrane in the presence of P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMonoglyceride lipase(Mouse)
University of California

Curated by ChEMBL
LigandPNGBDBM50132715(Dodecanesulfonyl fluoride | dodecane-1-sulfonyl fl...)
Affinity DataIC50: 200nMAssay Description:Inhibition of MAGL-mediated 2-arachidonoylglycerol hydrolysis in mouse brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Mouse)
University of California

Curated by ChEMBL
LigandPNGBDBM50132715(Dodecanesulfonyl fluoride | dodecane-1-sulfonyl fl...)
Affinity DataIC50: 2nMAssay Description:Inhibition of FAAH-mediated [3H]anandamide hydrolysis in mouse brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Mouse)
University of California

Curated by ChEMBL
LigandPNGBDBM50132715(Dodecanesulfonyl fluoride | dodecane-1-sulfonyl fl...)
Affinity DataIC50: 7nMAssay Description:Displacement of [3H]CP-55940 from CB1 receptor in mouse brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
University of Louvain

Curated by ChEMBL
LigandPNGBDBM50132715(Dodecanesulfonyl fluoride | dodecane-1-sulfonyl fl...)
Affinity DataIC50: 3nMAssay Description:Irreversible inhibition of fatty acid amide hydrolaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed