BDBM50132633 (2R,3S)-1-(4-Benzyloxy-benzenesulfonyl)-3-methyl-piperazine-2-carboxylic acid hydroxyamide::CHEMBL109833

SMILES C[C@@H]1NCCN([C@H]1C(=O)NO)S(=O)(=O)c1ccc(OCc2ccccc2)cc1

InChI Key InChIKey=SHBOXSNAYNDDGN-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50132633   

TargetInterstitial collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50132633((2R,3S)-1-(4-Benzyloxy-benzenesulfonyl)-3-methyl-p...)
Affinity DataIC50: 1.20E+4nMAssay Description:In vitro inhibition of matrix metalloprotease-1.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50132633((2R,3S)-1-(4-Benzyloxy-benzenesulfonyl)-3-methyl-p...)
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibition of human recombinant tumor necrosis factor-alpha converting enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50132633((2R,3S)-1-(4-Benzyloxy-benzenesulfonyl)-3-methyl-p...)
Affinity DataIC50: 11nMAssay Description:In vitro inhibition of matrix metalloprotease-13.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50132633((2R,3S)-1-(4-Benzyloxy-benzenesulfonyl)-3-methyl-p...)
Affinity DataIC50: 25nMAssay Description:Inhibition of human recombinant tumor necrosis factor-alpha converting enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed