BDBM50132631 (2R,3S)-3-Methyl-1-[4-(2-methyl-benzyloxy)-benzenesulfonyl]-piperazine-2-carboxylic acid hydroxyamide::CHEMBL112232

SMILES C[C@@H]1NCCN([C@H]1C(=O)NO)S(=O)(=O)c1ccc(OCc2ccccc2C)cc1

InChI Key InChIKey=IJIWBJJLSPLOBZ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50132631   

LigandPNGBDBM50132631((2R,3S)-3-Methyl-1-[4-(2-methyl-benzyloxy)-benzene...)
Affinity DataIC50: 19nMAssay Description:Inhibition of human recombinant tumor necrosis factor-alpha converting enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50132631((2R,3S)-3-Methyl-1-[4-(2-methyl-benzyloxy)-benzene...)
Affinity DataIC50: 19nMAssay Description:In vitro inhibition of matrix metalloprotease-13.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50132631((2R,3S)-3-Methyl-1-[4-(2-methyl-benzyloxy)-benzene...)
Affinity DataIC50: 1.20E+4nMAssay Description:In vitro inhibition of matrix metalloprotease-1.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50132631((2R,3S)-3-Methyl-1-[4-(2-methyl-benzyloxy)-benzene...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of Tumor necrosis factor-alpha (TNF-alpha) release in human whole bloodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed