BDBM50132626 (2R,3S)-4-Acetyl-1-[4-(2-ethyl-benzyloxy)-benzenesulfonyl]-3-methyl-piperazine-2-carboxylic acid hydroxyamide::CHEMBL109775

SMILES CCc1ccccc1COc1ccc(cc1)S(=O)(=O)N1CCN([C@@H](C)[C@@H]1C(=O)NO)C(C)=O

InChI Key InChIKey=DODLQVHRMPIMNB-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50132626   

TargetInterstitial collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50132626((2R,3S)-4-Acetyl-1-[4-(2-ethyl-benzyloxy)-benzenes...)
Affinity DataIC50: 6.70E+3nMAssay Description:In vitro inhibition of matrix metalloprotease-1.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50132626((2R,3S)-4-Acetyl-1-[4-(2-ethyl-benzyloxy)-benzenes...)
Affinity DataIC50: 40nMAssay Description:In vitro inhibition of matrix metalloprotease-13.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50132626((2R,3S)-4-Acetyl-1-[4-(2-ethyl-benzyloxy)-benzenes...)
Affinity DataIC50: 600nMAssay Description:Inhibition of human recombinant tumor necrosis factor-alpha converting enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50132626((2R,3S)-4-Acetyl-1-[4-(2-ethyl-benzyloxy)-benzenes...)
Affinity DataIC50: 7nMAssay Description:Inhibition of human recombinant tumor necrosis factor-alpha converting enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed