BDBM50132417 3-[1-(4-Dimethylamino-phenyl)-meth-(Z)-ylidene]-5-(thiophene-2-carbonyl)-1,3-dihydro-indol-2-one::CHEMBL105255

SMILES CN(C)c1ccc(\C=C2/C(=O)Nc3ccc(cc23)C(=O)c2cccs2)cc1

InChI Key InChIKey=GOPIQWAPDSIQCF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50132417   

TargetTyrosine-protein kinase JAK3(Human)
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50132417(3-[1-(4-Dimethylamino-phenyl)-meth-(Z)-ylidene]-5-...)
Affinity DataIC50: 200nMAssay Description:Inhibitory activity against Janus Kinase 3 protein tyrosine kinase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed