BDBM50132317 17,23-dimethyl-20-oxa-4,14,17,23,26-pentaazahexacyclo[24.6.1.17,14.02,6.08,13.027,32]tetratriaconta-1(33),2(6),7(34),8(13),9,11,27(32),28,30-nonaene-3,5-dione::CHEMBL105477

SMILES CN1CCOCCN(C)CCn2cc(C3=C(C(=O)NC3=O)c3cn(CC1)c1ccccc31)c1ccccc21

InChI Key InChIKey=JHWNRWTWKSNTOD-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50132317   

TargetProtein kinase C alpha type(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50132317(17,23-dimethyl-20-oxa-4,14,17,23,26-pentaazahexacy...)
Affinity DataIC50: 490nMAssay Description:Inhibition of Protein kinase C alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProtein kinase C beta type(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50132317(17,23-dimethyl-20-oxa-4,14,17,23,26-pentaazahexacy...)
Affinity DataIC50: 27nMAssay Description:Inhibition of Protein kinase C beta 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProtein kinase C epsilon type(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50132317(17,23-dimethyl-20-oxa-4,14,17,23,26-pentaazahexacy...)
Affinity DataIC50: 610nMAssay Description:Inhibition of Protein kinase C epsilonMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50132317(17,23-dimethyl-20-oxa-4,14,17,23,26-pentaazahexacy...)
Affinity DataIC50: 6nMAssay Description:Inhibition of Glycogen synthase kinase-3 betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProtein kinase C gamma type(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50132317(17,23-dimethyl-20-oxa-4,14,17,23,26-pentaazahexacy...)
Affinity DataIC50: 1.56E+3nMAssay Description:Inhibition of Protein kinase C gamma at 1 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50132317(17,23-dimethyl-20-oxa-4,14,17,23,26-pentaazahexacy...)
Affinity DataIC50: 6nMAssay Description:Inhibition of human GSK3-betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetProtein kinase C beta type(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50132317(17,23-dimethyl-20-oxa-4,14,17,23,26-pentaazahexacy...)
Affinity DataIC50: 41nMAssay Description:Inhibition of Protein kinase C beta 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed