BDBM50132265 4-[3-Chloro-4-(1-methyl-1H-imidazol-2-ylsulfanyl)-phenylamino]-6,7-diethoxy-quinoline-3-carbonitrile::CHEMBL321045

SMILES CCOc1cc2ncc(C#N)c(Nc3ccc(Sc4nccn4C)c(Cl)c3)c2cc1OCC

InChI Key InChIKey=GVWXQEVWTJEGNA-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50132265   

TargetDual specificity mitogen-activated protein kinase kinase 1(Human)
Wyeth Research

Curated by ChEMBL

LigandBDBM50132265(4-[3-Chloro-4-(1-methyl-1H-imidazol-2-ylsulfanyl)-...)Copy SMILESCopy InChI

Affinity DataIC50: 10nMAssay Description:Inhibitory concentration against Mitogen activated protein kinase kinase kinase 1 was determined using Raf/MEK1 coupled assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
11/10/2009
Entry Details Article
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