BDBM50132175 2-[(3-Isopropyl-1H-pyrazolo[4,3-d]pyrimidin-7-ylamino)-methyl]-phenol::CHEMBL101552
SMILES CC(C)c1[nH]nc2c(NCc3ccccc3O)ncnc12
InChI Key InChIKey=ZMLXUURZINLKCX-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50132175
TargetCyclin-dependent kinase 1/G2/mitotic-specific cyclin-B1/G2/mitotic-specific cyclin-B2/G2/mitotic-specific cyclin-B3(Human)
Academy of Sciences of The Czech Republic
Curated by ChEMBL
Academy of Sciences of The Czech Republic
Curated by ChEMBL
Affinity DataIC50: 440nMAssay Description:Inhibitory concentration against Cyclin-dependent kinase 1-cyclin BMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 1/G2/mitotic-specific cyclin-B1/G2/mitotic-specific cyclin-B2/G2/mitotic-specific cyclin-B3(Human)
Academy of Sciences of The Czech Republic
Curated by ChEMBL
Academy of Sciences of The Czech Republic
Curated by ChEMBL
Affinity DataIC50: 5.40E+4nMAssay Description:In vitro antiproliferative activity against myeloid leukemia K562 cell lineMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Human)
University of Kwazulu-Natal
Curated by ChEMBL
University of Kwazulu-Natal
Curated by ChEMBL
Affinity DataIC50: 440nMAssay Description:Inhibition of CDK1/CyclinB (unknown origin)More data for this Ligand-Target Pair