BDBM50132047 3-(4-Chloro-phenyl)-N-{4-[4-(2-methoxy-phenyl)-piperazin-1-yl]-butyl}-acrylamide; oxalic acid::CHEMBL1180455::CHEMBL126725

SMILES COc1ccccc1N1CCN(CCCCNC(=O)\C=C\c2ccc(Cl)cc2)CC1

InChI Key InChIKey=QQXFYZWQVQXWMO-UHFFFAOYSA-N

Data  4 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50132047   

TargetD(2) dopamine receptor(Human)
Johann Wolfgang Goethe-UniversitäT

Curated by ChEMBL
LigandPNGBDBM50132047(CHEMBL126725 | CHEMBL1180455 | 3-(4-Chloro-phenyl)...)
Affinity DataEC50:  10nMAssay Description:Effective concentration for Dopamine receptor D3 was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Johann Wolfgang Goethe-UniversitäT

Curated by ChEMBL
LigandPNGBDBM50132047(CHEMBL126725 | CHEMBL1180455 | 3-(4-Chloro-phenyl)...)
Affinity DataKi:  0.440nMAssay Description:Binding affinity for human dopamine receptor D3 by displacing [125I]iodosulpiride expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Johann Wolfgang Goethe-UniversitäT

Curated by ChEMBL
LigandPNGBDBM50132047(CHEMBL126725 | CHEMBL1180455 | 3-(4-Chloro-phenyl)...)
Affinity DataKi:  0.440nMAssay Description:Displacement of [3H]spiperone from human dopamine D3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Johann Wolfgang Goethe-UniversitäT

Curated by ChEMBL
LigandPNGBDBM50132047(CHEMBL126725 | CHEMBL1180455 | 3-(4-Chloro-phenyl)...)
Affinity DataKi:  22.6nMAssay Description:Binding affinity for human dopamine receptor D2 by displacing [125I]iodosulpiride expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Johann Wolfgang Goethe-UniversitäT

Curated by ChEMBL
LigandPNGBDBM50132047(CHEMBL126725 | CHEMBL1180455 | 3-(4-Chloro-phenyl)...)
Affinity DataKi:  22.6nMAssay Description:Displacement of [3H]spiperone from human dopamine D2long receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed