BDBM50132020 2-{3-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-propyl}-isoindole-1,3-dione; oxalic acid::CHEMBL127979::CHEMBL26853

SMILES COc1ccccc1N1CCN(CCCN2C(=O)c3ccccc3C2=O)CC1

InChI Key InChIKey=MDQWSMFPLDSLBV-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50132020   

Target5-hydroxytryptamine receptor 1A(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50132020(CHEMBL127979 | CHEMBL26853 | 2-{3-[4-(2-Methoxy-ph...)
Affinity DataKi:  20nMAssay Description:Compound was evaluated for its ability to displace [3H]8-OH-DPAT from serotonin 5-hydroxytryptamine 1A receptor in rat cerebral cortex membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

Target5-hydroxytryptamine receptor 1A(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50132020(CHEMBL127979 | CHEMBL26853 | 2-{3-[4-(2-Methoxy-ph...)
Affinity DataKi:  20nMAssay Description:Binding affinity of a compound to rat brain 5-hydroxytryptamine 1A (serotonin) receptor assayed by radiolabeled [3H]-8-OH-DPAT ligand displacementMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
LigandPNGBDBM50132020(CHEMBL127979 | CHEMBL26853 | 2-{3-[4-(2-Methoxy-ph...)
Affinity DataKi:  33nMAssay Description:Binding affinity at Alpha-1 adrenergic receptor in rat cerebral cortex membranes by [3H]prazosin displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetD(2) dopamine receptor(Human)
Johann Wolfgang Goethe-UniversitäT

Curated by ChEMBL
LigandPNGBDBM50132020(CHEMBL127979 | CHEMBL26853 | 2-{3-[4-(2-Methoxy-ph...)
Affinity DataKi:  300nMAssay Description:Binding affinity for human dopamine receptor D2 by displacing [125I]iodosulpiride expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Johann Wolfgang Goethe-UniversitäT

Curated by ChEMBL
LigandPNGBDBM50132020(CHEMBL127979 | CHEMBL26853 | 2-{3-[4-(2-Methoxy-ph...)
Affinity DataKi:  560nMAssay Description:Binding affinity for human dopamine receptor D3 by displacing [125I]iodosulpiride expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed