BDBM50131988 2-[1-(Benzothiazole-2-carbonyl)-4-guanidino-butylcarbamoyl]-pyrrolidine-1-sulfonic acid methyl ester; TFA::CHEMBL124809

SMILES COS(=O)(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(N)=N)C(=O)c1nc2ccccc2s1

InChI Key InChIKey=LIALTYGZACGKAO-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50131988   

TargetTrypsin-3(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50131988(2-[1-(Benzothiazole-2-carbonyl)-4-guanidino-butylc...)
Affinity DataIC50: 1nMAssay Description:Beta-Trypsin inhibitory activity of compound was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2012
Entry Details Article
PubMed
TargetTryptase beta-2(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50131988(2-[1-(Benzothiazole-2-carbonyl)-4-guanidino-butylc...)
Affinity DataKi:  33nMAssay Description:In vitro inhibition of human Tryptase beta.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2012
Entry Details Article
PubMed
TargetSerine protease 1(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50131988(2-[1-(Benzothiazole-2-carbonyl)-4-guanidino-butylc...)
Affinity DataKi:  38nMAssay Description:In vitro inhibition of bovine trypsin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2012
Entry Details Article
PubMed