BDBM50131981 CHEMBL340098::N-{[1-(Benzothiazole-2-carbonyl)-4-guanidino-butylcarbamoyl]-methyl}-acetamide; TFA

SMILES CC(=O)NCC(=O)N[C@@H](CCCNC(N)=N)C(=O)c1nc2ccccc2s1

InChI Key InChIKey=BWCCNYCMGLDNHH-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50131981   

TargetTrypsin-3(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50131981(N-{[1-(Benzothiazole-2-carbonyl)-4-guanidino-butyl...)
Affinity DataIC50: 2nMAssay Description:Beta-Trypsin inhibitory activity of compound was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2012
Entry Details Article
PubMed
TargetSerine protease 1(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50131981(N-{[1-(Benzothiazole-2-carbonyl)-4-guanidino-butyl...)
Affinity DataKi:  260nMAssay Description:In vitro inhibition of bovine trypsin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2012
Entry Details Article
PubMed
TargetTryptase beta-2(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50131981(N-{[1-(Benzothiazole-2-carbonyl)-4-guanidino-butyl...)
Affinity DataKi:  470nMAssay Description:In vitro inhibition of human Tryptase beta.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2012
Entry Details Article
PubMed