BDBM50131971 CHEMBL338393::Thiophene-2-carboxylic acid methyl-[2-(1-methyl-5-phenyl-2,3-dihydro-1H-benzo[e][1,4]diazepin-2-yl)-ethyl]-amide

SMILES CN(CCC1CN=C(c2ccccc2)c2ccccc2N1C)C(=O)c1cccs1

InChI Key InChIKey=CKGHAUDWGMFVJT-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50131971   

TargetKappa-type opioid receptor(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50131971(Thiophene-2-carboxylic acid methyl-[2-(1-methyl-5-...)
Affinity DataKi:  4.30nMAssay Description:Binding affinity against opioid receptor kappa 1 from human cloned receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50131971(Thiophene-2-carboxylic acid methyl-[2-(1-methyl-5-...)
Affinity DataKi:  4.40nMAssay Description:Binding constant towards human Opioid receptor kappa 1 was reportedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50131971(Thiophene-2-carboxylic acid methyl-[2-(1-methyl-5-...)
Affinity DataKi:  26nMAssay Description:Binding affinity determined against Opioid receptor kappa 1 from a native receptor in guinea pigMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2012
Entry Details Article
PubMed