BDBM50131966 CHEMBL126596::Thiophene-2-carboxylic acid [2-(6-methoxy-1-methyl-5-phenyl-2,3-dihydro-1H-benzo[e][1,4]diazepin-2-yl)-ethyl]-amide

SMILES COc1cccc2N(C)C(CCNC(=O)c3cccs3)CN=C(c3ccccc3)c12

InChI Key InChIKey=VJLJZUZTFVRPGO-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50131966   

TargetKappa-type opioid receptor(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50131966(Thiophene-2-carboxylic acid [2-(6-methoxy-1-methyl...)
Affinity DataKi:  3.80nMAssay Description:Binding affinity against opioid receptor kappa 1 from human cloned receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50131966(Thiophene-2-carboxylic acid [2-(6-methoxy-1-methyl...)
Affinity DataKi:  116nMAssay Description:Binding affinity determined against Opioid receptor kappa 1 from a native receptor in guinea pigMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50131966(Thiophene-2-carboxylic acid [2-(6-methoxy-1-methyl...)
Affinity DataKi:  116nMAssay Description:Binding affinity determined against Opioid receptor kappa 1 from a native receptor in guinea pigMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2012
Entry Details Article
PubMed