BDBM50131909 1-((2R,4R,5S)-4-aminomethyl-5-hydroxymethyl-tetrahydro-furan-2-yl)-5-methyl-1H-pyrimidine-2,4-dione::1-(4-Aminomethyl-5-hydroxymethyl-tetrahydro-furan-2-yl)-5-methyl-1H-pyrimidine-2,4-dione::CHEMBL341264

SMILES Cc1cn([C@H]2C[C@H](CN)[C@@H](CO)O2)c(=O)[nH]c1=O

InChI Key InChIKey=WEMWNHDMPLAIPE-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50131909   

TargetThymidylate kinase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50131909(1-(4-Aminomethyl-5-hydroxymethyl-tetrahydro-furan-...)
Affinity DataKi:  5.70E+4nMAssay Description:In Vitro inhibition of Thymidine Monophosphatase Kinase of Mycobacterium tuberculosis (TMPKm)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2012
Entry Details Article
PubMed
TargetThymidylate kinase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50131909(1-(4-Aminomethyl-5-hydroxymethyl-tetrahydro-furan-...)
Affinity DataKi:  5.70E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis TMPK by coupled spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
TargetThymidine kinase, cytosolic(Human)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50131909(1-(4-Aminomethyl-5-hydroxymethyl-tetrahydro-furan-...)
Affinity DataKi:  2.20E+5nMAssay Description:In Vitro inhibition of Thymidine Monophosphatase Kinase (TMPKh)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2012
Entry Details Article
PubMed
TargetThymidylate kinase(Human)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50131909(1-(4-Aminomethyl-5-hydroxymethyl-tetrahydro-furan-...)
Affinity DataKi:  2.20E+5nMAssay Description:Inhibition of human TMPK by coupled spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed