BDBM50131908 1-(4-Azidomethyl-5-hydroxymethyl-tetrahydro-furan-2-yl)-5-methyl-1H-pyrimidine-2,4-dione::CHEMBL340604

SMILES Cc1cn([C@H]2C[C@H](CN=[N+]=[N-])[C@@H](CO)O2)c(=O)[nH]c1=O

InChI Key InChIKey=SZDHPCIIVLDJJD-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50131908   

TargetThymidylate kinase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50131908(1-(4-Azidomethyl-5-hydroxymethyl-tetrahydro-furan-...)
Affinity DataKi:  4.00E+4nMAssay Description:In Vitro inhibition of Thymidine Monophosphatase Kinase of Mycobacterium tuberculosis (TMPKm)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2012
Entry Details Article
PubMed
TargetThymidylate kinase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50131908(1-(4-Azidomethyl-5-hydroxymethyl-tetrahydro-furan-...)
Affinity DataKi:  4.00E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis TMPK assessed as inhibition constant by coupled spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetThymidine kinase, cytosolic(Human)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50131908(1-(4-Azidomethyl-5-hydroxymethyl-tetrahydro-furan-...)
Affinity DataKi:  1.04E+6nMAssay Description:In Vitro inhibition of Thymidine Monophosphatase Kinase (TMPKh)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2012
Entry Details Article
PubMed