BDBM50131885 4,8-diaza-3 (1,4) , 9 (4,1)-dipyridina-1 (1,4), 6 (1,3) -dibenzenacyclodecaphan-3,9-bis (ilium) dibromide::CHEMBL125148

SMILES C1N[c+]2ccn(Cc3ccc(Cn4cc[c+](NCc5cccc1c5)cc4)cc3)cc2

InChI Key InChIKey=YCCMJVNGFYJMAD-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50131885   

TargetCholine kinase alpha(Human)
Universidad De Granada

Curated by ChEMBL
LigandPNGBDBM50131885(4,8-diaza-3 (1,4) , 9 (4,1)-dipyridina-1 (1,4), 6 ...)
Affinity DataIC50: 300nMAssay Description:Ex vivo inhibitory activity against human choline kinase was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCholine kinase alpha(Human)
Universidad De Granada

Curated by ChEMBL
LigandPNGBDBM50131885(4,8-diaza-3 (1,4) , 9 (4,1)-dipyridina-1 (1,4), 6 ...)
Affinity DataIC50: 300nMAssay Description:Inhibition of ChoK in HT29 cells using [methyl-14C]choline chloride as substrate after 14 hrs by radiographyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetAcetylcholinesterase(Bovine)
Universidad De Granada

Curated by ChEMBL
LigandPNGBDBM50131885(4,8-diaza-3 (1,4) , 9 (4,1)-dipyridina-1 (1,4), 6 ...)
Affinity DataIC50: 4.80E+3nMAssay Description:Inhibition of bovine AChE after 20 mins using acetylthiocholine iodide as a substrate by Ellman's assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Horse)
Universidad De Granada

Curated by ChEMBL
LigandPNGBDBM50131885(4,8-diaza-3 (1,4) , 9 (4,1)-dipyridina-1 (1,4), 6 ...)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of equine BChE after 20 mins using butyrylthiocholine iodide as a substrate by Ellman's assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed