BDBM50131856 CHEMBL3633365

SMILES N[C@@H](CSC1(c2ccc(cc2)C(F)(F)F)c2ccccc2CCc2ccccc12)C(O)=O

InChI Key InChIKey=WBOSHVRLUFZOTA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50131856   

TargetKinesin-like protein KIF11(Human)
University of Shizuoka

Curated by ChEMBL
LigandPNGBDBM50131856(CHEMBL3633365)
Affinity DataIC50: 21nMAssay Description:Inhibition of His-tagged KSP motor domain (1 to 369) (unknown origin) assessed as inhibition of microtubule-stimulated KSP ATPase activity preincuabt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2016
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
University of Shizuoka

Curated by ChEMBL
LigandPNGBDBM50131856(CHEMBL3633365)
Affinity DataIC50: 21nMAssay Description:Inhibition C-terminal His-tagged KSP motor domain(1 to 369 residues) (unknown origin) expressed in bacteria assessed as inhibition of microtubule-sti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed