BDBM50131814 CHEMBL3634598

SMILES Cc1cc2c(cc1Cl)N(C(=O)O2)CCC(=O)O

InChI Key InChIKey=QPMPFAMMRAXUAV-UHFFFAOYSA-N

Data  3 IC50

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50131814   

TargetKynurenine 3-monooxygenase(Human)
Therachem Research Medilab (India)

Curated by ChEMBL
LigandPNGBDBM50131814(CHEMBL3634598)
Affinity DataIC50: 13nMAssay Description:Inhibition of kynurenine monooxygenase (unknown origin) by MS rapidfire assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2016
Entry Details Article
PubMed
TargetKynurenine 3-monooxygenase(Human)
Therachem Research Medilab (India)

Curated by ChEMBL
LigandPNGBDBM50131814(CHEMBL3634598)
Affinity DataIC50: 631nMAssay Description:Inhibition of full length human KMO expressed in HEK293 cells using kynurenine as substrate measured after 20 hrs by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/14/2020
Entry Details Article
PubMed
TargetKynurenine 3-monooxygenase(Human)
Therachem Research Medilab (India)

Curated by ChEMBL
LigandPNGBDBM50131814(CHEMBL3634598)
Affinity DataIC50: 13nMAssay Description:Inhibition of full length human GST-tagged KMO expressed in baculovirus infected Sf9 insect cell membranes using kynurenine as substrate measured aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/14/2020
Entry Details Article
PubMed