BDBM50131810 CHEMBL3634602

SMILES C[C@@H](Oc1cc2oc(=O)n(CCC(O)=O)c2cc1Cl)c1cccnn1

InChI Key InChIKey=NEIWTLNQTVXJFF-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50131810   

TargetKynurenine 3-monooxygenase(Human)
Therachem Research Medilab (India)

Curated by ChEMBL
LigandPNGBDBM50131810(CHEMBL3634602)
Affinity DataIC50: 794nMAssay Description:Inhibition of kynurenine monooxygenase (unknown origin) by MS rapidfire assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2016
Entry Details Article
PubMed
TargetKynurenine 3-monooxygenase(Human)
Therachem Research Medilab (India)

Curated by ChEMBL
LigandPNGBDBM50131810(CHEMBL3634602)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of full length human GST-tagged KMO expressed in baculovirus infected Sf9 insect cell membranes using kynurenine as substrate measured aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/14/2020
Entry Details Article
PubMed
TargetKynurenine 3-monooxygenase(Human)
Therachem Research Medilab (India)

Curated by ChEMBL
LigandPNGBDBM50131810(CHEMBL3634602)
Affinity DataIC50: 631nMAssay Description:Inhibition of full length human KMO expressed in HEK293 cells using kynurenine as substrate measured after 20 hrs by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/14/2020
Entry Details Article
PubMed