BDBM50131701 CHEMBL3633522

SMILES CC(C)NC1CN(C1)c1c(F)cc2c(c1C)n(cc(C(O)=O)c2=O)-c1nc(N)c(F)cc1F

InChI Key InChIKey=MJMVUQNNSOBCGF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50131701   

TargetDNA gyrase A/A/B/B tetramer(Escherichia coli (strain K12))
Wakunaga Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50131701(CHEMBL3633522)
Affinity DataIC50: 433nMAssay Description:Inhibition of Escherichia coli DNA gyrase preincubated for 5 mins at 37 degC before addition of relaxed pBR322 as substrate by supercoiling assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2016
Entry Details Article
PubMed