BDBM50131697 CHEMBL3633320

SMILES [O-][N+](=O)c1ncn(CC(=O)N2CCN(Cc3ccc(cc3)C(F)(F)F)CC2)n1

InChI Key InChIKey=GARYHNNCUAMEQJ-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50131697   

TargetCytochrome P450 3A4(Human)
Northshore University Healthsystem

Curated by ChEMBL
LigandPNGBDBM50131697(CHEMBL3633320)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of CYP3A4 in human Liver microsomes after 5 mins by LC-MS/MS methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2016
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Northshore University Healthsystem

Curated by ChEMBL
LigandPNGBDBM50131697(CHEMBL3633320)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of CYP2C9 in human Liver microsomes after 5 mins by LC-MS/MS methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2016
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Northshore University Healthsystem

Curated by ChEMBL
LigandPNGBDBM50131697(CHEMBL3633320)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of CYP2D6 in human Liver microsomes after 5 mins by LC-MS/MS methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2016
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
Northshore University Healthsystem

Curated by ChEMBL
LigandPNGBDBM50131697(CHEMBL3633320)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of CYP2C19 in human Liver microsomes after 35 mins by LC-MS/MS methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2016
Entry Details Article
PubMed
TargetCytochrome P450 2C8(Human)
Northshore University Healthsystem

Curated by ChEMBL
LigandPNGBDBM50131697(CHEMBL3633320)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of CYP2C8 in human Liver microsomes after 5 mins by LC-MS/MS methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2016
Entry Details Article
PubMed