BDBM50131533 3-[(4-But-2-ynyloxy-benzenesulfonyl)-methyl-amino]-N-hydroxy-propionamide::CHEMBL96419

SMILES CC#CCOc1ccc(cc1)S(=O)(=O)N(C)CCC(=O)NO

InChI Key InChIKey=RWOPWLLDIYQNCW-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50131533   

TargetMatrix metalloproteinase-9(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50131533(3-[(4-But-2-ynyloxy-benzenesulfonyl)-methyl-amino]...)
Affinity DataIC50: 53nMAssay Description:Inhibition of Matrix metalloprotein-9 at 10 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50131533(3-[(4-But-2-ynyloxy-benzenesulfonyl)-methyl-amino]...)
Affinity DataIC50: 33nMAssay Description:Inhibition of Matrix metalloprotein 1 at 10 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50131533(3-[(4-But-2-ynyloxy-benzenesulfonyl)-methyl-amino]...)
Affinity DataIC50: 73nMAssay Description:In vitro inhibition of tumor necrosis factor-alpha converting enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50131533(3-[(4-But-2-ynyloxy-benzenesulfonyl)-methyl-amino]...)
Affinity DataIC50: 57nMAssay Description:In vitro inhibition of Matrix metalloprotein 13More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed