BDBM50131526 (R)-2-(4-(but-2-ynyloxy)-N-methylphenylsulfonamido)-N-hydroxy-2-(4-(2-(methylamino)ethoxy)phenyl)acetamide::(R)-2-[(4-But-2-ynyloxy-benzenesulfonyl)-methyl-amino]-N-hydroxy-2-[4-(2-methylamino-ethoxy)-phenyl]-acetamide::CHEMBL98061

SMILES CNCCOc1ccc(cc1)[C@@H](N(C)S(=O)(=O)c1ccc(OCC#CC)cc1)C(=O)NO

InChI Key InChIKey=QCHHXEMLMRDLDA-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50131526   

TargetMatrix metalloproteinase-9(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50131526((R)-2-[(4-But-2-ynyloxy-benzenesulfonyl)-methyl-am...)
Affinity DataIC50: 11nMAssay Description:In vitro inhibition of Matrix metalloprotein-9More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50131526((R)-2-[(4-But-2-ynyloxy-benzenesulfonyl)-methyl-am...)
Affinity DataIC50: 927nMAssay Description:In vitro inhibition of Matrix metalloprotein 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50131526((R)-2-[(4-But-2-ynyloxy-benzenesulfonyl)-methyl-am...)
Affinity DataIC50: 26nMAssay Description:In vitro inhibition of tumor necrosis factor-alpha converting enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50131526((R)-2-[(4-But-2-ynyloxy-benzenesulfonyl)-methyl-am...)
Affinity DataIC50: 27nMAssay Description:In vitro inhibition of Matrix metalloprotein 13More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50131526((R)-2-[(4-But-2-ynyloxy-benzenesulfonyl)-methyl-am...)
Affinity DataIC50: 933nMAssay Description:Inhibition of MMP1More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50131526((R)-2-[(4-But-2-ynyloxy-benzenesulfonyl)-methyl-am...)
Affinity DataIC50: 11nMAssay Description:Inhibition of MMP9More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed