BDBM50131520 2-(4-(but-2-ynyloxy)phenylsulfonamido)-N-hydroxy-3-methyl-3-(pyridin-3-ylmethylthio)butanamide::2-(4-But-2-ynyloxy-benzenesulfonylamino)-N-hydroxy-3-methyl-3-(pyridin-3-ylmethylsulfanyl)-butyramide::CHEMBL316928

SMILES CC#CCOc1ccc(cc1)S(=O)(=O)NC(C(=O)NO)C(C)(C)SCc1cccnc1

InChI Key InChIKey=AYPPVQRNMZPQMU-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50131520   

TargetMatrix metalloproteinase-9(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50131520(2-(4-But-2-ynyloxy-benzenesulfonylamino)-N-hydroxy...)
Affinity DataIC50: 130nMAssay Description:In vitro inhibition of Matrix metalloprotein-9More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50131520(2-(4-But-2-ynyloxy-benzenesulfonylamino)-N-hydroxy...)
Affinity DataIC50: 6nMAssay Description:In vitro inhibition of tumor necrosis factor-alpha converting enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50131520(2-(4-But-2-ynyloxy-benzenesulfonylamino)-N-hydroxy...)
Affinity DataIC50: 8nMAssay Description:In vitro inhibition of Matrix metalloprotein 13More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50131520(2-(4-But-2-ynyloxy-benzenesulfonylamino)-N-hydroxy...)
Affinity DataIC50: 476nMAssay Description:In vitro inhibition of Matrix metalloprotein 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50131520(2-(4-But-2-ynyloxy-benzenesulfonylamino)-N-hydroxy...)
Affinity DataIC50: 479nMAssay Description:Inhibition of MMP1More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50131520(2-(4-But-2-ynyloxy-benzenesulfonylamino)-N-hydroxy...)
Affinity DataIC50: 129nMAssay Description:Inhibition of MMP9More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed