BDBM50131395 4-[2-(4,4-Difluoro-2-{[(2S,4R)-1-((S)-2-isobutoxycarbonylamino-3-methyl-butyryl)-4-(7-methoxy-2-phenyl-quinolin-4-yloxy)-pyrrolidine-2-carbonyl]-amino}-butyrylamino)-ethyl]-benzoic acid::CHEMBL421380

SMILES COc1ccc2c(O[C@@H]3C[C@H](N(C3)C(=O)[C@@H](NC(=O)OCC(C)C)C(C)C)C(=O)NC(CC(F)F)C(=O)NCCc3ccc(cc3)C(O)=O)cc(nc2c1)-c1ccccc1

InChI Key InChIKey=RJXGGMVKFQHMCK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50131395   

TargetGenome polyprotein(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Mrl Rome

Curated by ChEMBL
LigandPNGBDBM50131395(4-[2-(4,4-Difluoro-2-{[(2S,4R)-1-((S)-2-isobutoxyc...)
Affinity DataIC50: 400nMAssay Description:Inhibitory concentration against hepatitis C virus (HCV) NS3 proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed