BDBM50130929 CHEMBL3633189

SMILES NC(=N)c1ccc(Nc2ncnc(Nc3ccc(cc3)C#N)c2[N+]([O-])=O)cc1

InChI Key InChIKey=SHIUJOLGVWYPDY-UHFFFAOYSA-N

Data  1 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50130929   

TargetProtein arginine N-methyltransferase 6(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50130929(CHEMBL3633189)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of PRMT6 (unknown origin) using biotinylated histone H4-derived peptide as substrate after 60 mins by AlphaLISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2016
Entry Details Article
PubMed
TargetProtein arginine N-methyltransferase 5(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50130929(CHEMBL3633189)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of PRMT5 (unknown origin) using biotinylated histone H4-derived peptide as substrate after 60 mins by AlphaLISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2016
Entry Details Article
PubMed
TargetHistone-arginine methyltransferase CARM1(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50130929(CHEMBL3633189)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PRMT4 (unknown origin) using biotinylated histone H4-derived peptide as substrate after 60 mins by AlphaLISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2016
Entry Details Article
PubMed
TargetProtein arginine N-methyltransferase 1 [11-371](Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50130929(CHEMBL3633189)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of PRMT1 (unknown origin) using biotinylated histone H4-derived peptide as substrate after 60 mins by AlphaLISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2016
Entry Details Article
PubMed
TargetProtein arginine N-methyltransferase 1 [11-371](Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50130929(CHEMBL3633189)
Affinity DataKi:  1.70E+3nMAssay Description:Non-competitive inhibition of PRMT1 (unknown origin) using biotinylated histone H4-derived peptide as substrate by Michaelis-Menten kinetic equation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2016
Entry Details Article
PubMed